Waklert is a generic form of Armodafinil (AKA r-Modafinil). Manufactured and distributed globally by Sun Pharmaceuticals Laboratory, Waklert has found popularity as one of the two most popular generic Armodafinil brands, along side our Artvigil by Hab Pharmaceuticals.
Lasts longer than Modafinil , Motivation , Memory , Alertness , Reaction time , Enjoyment & Wellbeing [12
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Once Armodafinil was officially announced in 2007, many long term Modafinil users were switched over to the newer, longer lasting version. However, with many most countries charging a hefty price for popular, USA based brand; Nuvigil. The market for cheaper generic forms of Armodafinil was discovered.
Armodafinil was first officially marketed as Nuvigil by Cephalon inc, being an enantiopure form of Modafinil, with only the (R)-enantiomer of Modafinil present in the formulation.
What does this mean?
It is not uncommon for drugs to be prepared in whats called a “recemic mixture”. This means that within the formulation, there will be two version or isomers of the drug. Often these two version are called the (R) and (S) isomer. Once the drug is consumed, both isomers will begin to act within the body.
Without going into too much pharmacological detail, having a recemic mixture of a drug is sometimes easier and more stable to produce. Often, the racemic mixture can be more pharmacologically active than the non-racemic mixture, but not always.
As an example, Ibuprofen is prepared and sold in a racemic mixture, containing (R)-ibuprofen and (S)-ibuprofen.
Armodafinil is a non-racemic drug. So within the Waklert pills, only the (R) isomer of Modafinil exists, and this is what gives it the name r-modafinil or Armodafinil.
So what’s so special about the (R) isomer of Modafinil? Well, it has a biologically longer half life than the (S) isomer, meaning it’s active within the body for a longer duration, 15 hours to be more specific. The (S) isomer has a bilogical half life of only 4 hours.
As an added bonus, it was discovered that Armodafinil is able to maintaing that wakeful feeling during the later stages of the day when compared with Modafinil, with up to 40% more plasma concentration of the drug identified .
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